MolNFT v1 · #419580 · protein

AlphaFold monomer V2.0 prediction for S-adenosylhomocysteine hydrolase-like protein 1 (O43865)

O43865: “AlphaFold monomer V2.0 prediction for S-adenosylhomocysteine hydrolase-like protein 1 (O43865)”. 6 pockets (best druggability 0.75). MolNFT v1 #419580 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: O43865
Type: protein
Length: 530 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7a1388B6Aad67B04634A32f63b8A6D6005eab86c
Molecule: S-adenosylhomocysteine hydrolase-like protein 1
UniProt: O43865
Pockets: 6 · best druggability 0.75

Structure

1 distinct chain · 40% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	S-adenosylhomocysteine hydrolase-like protein 1	protein	530	40% helix, 14% strand	O43865

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	624	0.75	0.82	71	empty
2	316	0.63	0.79	38	empty
3	449	0.61	0.76	51	empty
4	106	0.36	0.74	15	empty
5	54	0.31	0.75	12	empty

Compared structures

3MTG · Crystal structure of human S-adenosyl homocysteine hydrolase-like 1 protein · an experimental structure of the same protein · chain A against A, TM-score 0.69
3MTG · Crystal structure of human S-adenosyl homocysteine hydrolase-like 1 protein · an experimental structure of the same protein · chain A against A, TM-score 0.69

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O43865
Elsewhere: UniProt O43865 · AlphaFold DB O43865

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