MolNFT v1 · #419242 · protein

AlphaFold monomer V2.0 prediction for electroneutral sodium bicarbonate exchanger 1 (Q2Y0W8)

Q2Y0W8: “AlphaFold monomer V2.0 prediction for electroneutral sodium bicarbonate exchanger 1 (Q2Y0W8)”. 16 pockets (best druggability 0.73). MolNFT v1 #419242 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q2Y0W8
Type: protein
Length: 1,093 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x40B9C9d5F084D34d026E9d5Dd10501AcdF6d6152
Molecule: Electroneutral sodium bicarbonate exchanger 1
UniProt: Q2Y0W8
Pockets: 16 · best druggability 0.73

Structure

1 distinct chain · 47% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Electroneutral sodium bicarbonate exchanger 1	protein	1093	47% helix, 9% strand	Q2Y0W8

Pockets

16 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	754	0.73	0.79	77	empty
2	863	0.72	0.77	93	empty
3	280	0.67	0.82	46	empty
4	252	0.54	0.77	26	empty
5	206	0.49	0.75	27	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

5JHO · Crystal structure of the regulatory domain of the sodium driven chloride bicarbonate… · an experimental structure of the same protein · chain A against A, TM-score 0.22
5JHO · Crystal structure of the regulatory domain of the sodium driven chloride bicarbonate… · an experimental structure of the same protein · chain A against A, TM-score 0.22

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q2Y0W8
Elsewhere: UniProt Q2Y0W8 · AlphaFold DB Q2Y0W8

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