MolNFT v1 · #418867 · protein
AlphaFold monomer V2.0 prediction for SODIUM/NUCLEOSIDE cotransporter 2 (O88627)
O88627: “AlphaFold monomer V2.0 prediction for SODIUM/NUCLEOSIDE cotransporter 2 (O88627)”. 9 pockets (best druggability 0.71). MolNFT v1 #418867 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O88627
- Type
- protein
- Length
- 660 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xD61E4B2Abb763e7149629bfc7B900FA271E466d5
- Molecule
- SODIUM/NUCLEOSIDE cotransporter 2
- UniProt
- O88627
- Pockets
- 9 · best druggability 0.71
Structure
1 distinct chain · 69% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SODIUM/NUCLEOSIDE cotransporter 2 | protein | 660 | 69% helix, 1% strand | O88627 |
Pockets
9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 448 | 0.71 | 0.81 | 44 | empty |
| 2 | 552 | 0.65 | 0.75 | 41 | empty |
| 3 | 234 | 0.52 | 0.75 | 26 | empty |
| 4 | 131 | 0.51 | 0.80 | 22 | empty |
| 5 | 84 | 0.40 | 0.78 | 17 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O88627
- Elsewhere: UniProt O88627 · AlphaFold DB O88627
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