MolNFT v1 · #418866 · protein
AlphaFold monomer V2.0 prediction for SODIUM/NUCLEOSIDE cotransporter 2 (O43868)
O43868: “AlphaFold monomer V2.0 prediction for SODIUM/NUCLEOSIDE cotransporter 2 (O43868)”. 10 pockets (best druggability 0.70). MolNFT v1 #418866 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O43868
- Type
- protein
- Length
- 658 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x025f3b1a898b05AD2731bE6Ab72687b5920c4A3F
- Molecule
- SODIUM/NUCLEOSIDE cotransporter 2
- UniProt
- O43868
- Pockets
- 10 · best druggability 0.70
Structure
1 distinct chain · 69% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SODIUM/NUCLEOSIDE cotransporter 2 | protein | 658 | 69% helix, 1% strand | O43868 |
Pockets
10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 394 | 0.70 | 0.81 | 48 | empty |
| 2 | 538 | 0.66 | 0.76 | 45 | empty |
| 3 | 189 | 0.57 | 0.80 | 31 | empty |
| 4 | 189 | 0.49 | 0.75 | 21 | empty |
| 5 | 207 | 0.49 | 0.76 | 35 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43868
- Elsewhere: UniProt O43868 · AlphaFold DB O43868
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