MolNFT v1 · #418431 · protein
AlphaFold monomer V2.0 prediction for solute carrier family 12 member 2 (P55012)
P55012: “AlphaFold monomer V2.0 prediction for solute carrier family 12 member 2 (P55012)”. 20 pockets (best druggability 0.61). MolNFT v1 #418431 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P55012
- Type
- protein
- Length
- 1,205 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf9BD33f98eaEF245525fFf103d2CCb61Dcb4e196
- Molecule
- Solute carrier family 12 member 2
- UniProt
- P55012
- Pockets
- 20 · best druggability 0.61
Structure
1 distinct chain · 46% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Solute carrier family 12 member 2 | protein | 1205 | 46% helix, 6% strand | P55012 |
Pockets
20 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 263 | 0.61 | 0.80 | 38 | empty |
| 2 | 299 | 0.60 | 0.78 | 33 | empty |
| 3 | 177 | 0.59 | 0.82 | 27 | empty |
| 4 | 271 | 0.57 | 0.77 | 29 | empty |
| 5 | 187 | 0.56 | 0.80 | 21 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P55012
- Elsewhere: UniProt P55012 · AlphaFold DB P55012
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