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MolNFT v1 · #418299 · protein

AlphaFold monomer V2.0 prediction for transcriptional regulatory protein RXT2 (P38255)

P38255: “AlphaFold monomer V2.0 prediction for transcriptional regulatory protein RXT2 (P38255)”. 2 pockets (best druggability 0.40). MolNFT v1 #418299 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P38255
Type
protein
Length
430 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x7c75F0f7d6d136A2b8D4C6C6e9b3D8a697949DF1
Molecule
Transcriptional regulatory protein RXT2
UniProt
P38255
Pockets
2 · best druggability 0.40

Structure

1 distinct chain · 41% helix, 3% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATranscriptional regulatory protein RXT2protein43041% helix, 3% strandP38255

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1920.400.7714empty
2760.310.7414empty

Compared structures

  • 8HPO · Cryo-EM structure of a SIN3/HDAC complex from budding yeast · an experimental structure of the same protein · chain A against E, TM-score 0.33

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