MolNFT v1 · #411376 · protein
AlphaFold monomer V2.0 prediction for ribosomal RNA small subunit methyltransferase a (O67680)
O67680: “AlphaFold monomer V2.0 prediction for ribosomal RNA small subunit methyltransferase a (O67680)”. 3 pockets (best druggability 0.76). MolNFT v1 #411376 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O67680
- Type
- protein
- Length
- 248 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5BeA89782341f98147F2D811B063F91F0aE7D7bF
- Molecule
- Ribosomal RNA small subunit methyltransferase a
- UniProt
- O67680
- Pockets
- 3 · best druggability 0.76
Structure
1 distinct chain · 39% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribosomal RNA small subunit methyltransferase a | protein | 248 | 39% helix, 20% strand | O67680 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 208 | 0.76 | 0.91 | 38 | empty |
| 2 | 90 | 0.44 | 0.79 | 13 | empty |
| 3 | 63 | 0.29 | 0.74 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 3FTF · Crystal structure of a. aeolicus ksga in complex with RNA and sah · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 3FTF · Crystal structure of A. aeolicus KsgA in complex with RNA and SAH · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 3FTD · Crystal structure of A. aeolicus KsgA at 1.44-Angstrom resolution · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 3FTD · Crystal structure of a. aeolicus ksga at 1.44-ångström resolution · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 3R9X · Crystal structure of Era in complex with MgGDPNP, nucleotides 1506-1542 of 16S ribosomal… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 3R9X · Crystal structure of era in complex with mggdpnp, nucleotides 1506- 1542 of 16S ribosomal… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 3FTC · Crystal structure of A. aeolicus KsgA at 1.72-Angstrom resolution · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 3FTC · Crystal structure of a. aeolicus ksga at 1.72-ångström resolution · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 3FTE · Crystal structure of A. aeolicus KsgA in complex with RNA · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 3FTE · Crystal structure of a. aeolicus ksga in complex with RNA · an experimental structure of the same protein · chain A against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O67680
- Elsewhere: UniProt O67680 · AlphaFold DB O67680
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