MolNFT v1 · #39407 · protein
AlphaFold monomer V2.0 prediction for activin receptor type-2A (Q28043)
Q28043: “AlphaFold monomer V2.0 prediction for activin receptor type-2A (Q28043)”. 4 pockets (best druggability 0.70). MolNFT v1 #39407 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q28043
- Type
- protein
- Length
- 513 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9248A6a2Adb75e0b630150924b6a8d168C063c9a
- Molecule
- Activin receptor type-2A
- UniProt
- Q28043
- Pockets
- 4 · best druggability 0.70
Structure
1 distinct chain · 37% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Activin receptor type-2A | protein | 513 | 37% helix, 21% strand | Q28043 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 437 | 0.70 | 0.81 | 47 | empty |
| 2 | 140 | 0.40 | 0.74 | 24 | empty |
| 3 | 61 | 0.31 | 0.75 | 15 | empty |
| 4 | 62 | 0.30 | 0.75 | 13 | empty |
Modifications
Observed in the structure: 5 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q28043
- Elsewhere: UniProt Q28043 · AlphaFold DB Q28043
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.