MolNFT v1 · #392148 · protein

AlphaFold monomer V2.0 prediction for RAS-related GTP-binding protein C (Q99K70)

Q99K70: “AlphaFold monomer V2.0 prediction for RAS-related GTP-binding protein C (Q99K70)”. 4 pockets (best druggability 0.53). MolNFT v1 #392148 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q99K70
Type: protein
Length: 398 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x822E012D889323C46BeB0B18E712e15c69cF5f87
Molecule: RAS-related GTP-binding protein C
UniProt: Q99K70
Pockets: 4 · best druggability 0.53

Structure

1 distinct chain · 36% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RAS-related GTP-binding protein C	protein	398	36% helix, 17% strand	Q99K70

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	232	0.53	0.76	26	empty
2	51	0.49	0.87	14	empty
3	152	0.48	0.78	26	empty
4	55	0.30	0.76	16	empty

Compared structures

5X6V · Crystal structure of human heteroheptameric complex · an experimental structure of the same protein · chain A against G, TM-score 0.33
5X6V · Crystal structure of human heteroheptameric complex · an experimental structure of the same protein · chain A against G, TM-score 0.33

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q99K70
Elsewhere: UniProt Q99K70 · AlphaFold DB Q99K70

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