GL1X · GenesisL1 explorer

MolNFT v1 · #388859 · protein

AlphaFold monomer V2.0 prediction for ecf RNA polymerase sigma-E factor (P0AGB6)

P0AGB6: “AlphaFold monomer V2.0 prediction for ecf RNA polymerase sigma-E factor (P0AGB6)”. 2 pockets (best druggability 0.65). MolNFT v1 #388859 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P0AGB6
Type
protein
Length
191 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xf946795cBBF0d709882f916b7A64276982c26588
Molecule
Ecf RNA polymerase sigma-E factor
UniProt
P0AGB6
Pockets
2 · best druggability 0.65

Structure

1 distinct chain · 68% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AEcf RNA polymerase sigma-E factorprotein19168% helix, 0% strandP0AGB6

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16850.650.7559empty
2520.290.7614empty

Compared structures

  • 1OR7 · Crystal structure of escherichia COLI sigmae with the cytoplasmic domain of its… · an experimental structure of the same protein · chain A against A, TM-score 0.48
  • 1OR7 · Crystal Structure of Escherichia coli sigmaE with the Cytoplasmic Domain of its… · an experimental structure of the same protein · chain A against A, TM-score 0.48
  • 5OR5 · NMR structure of the complex formed by an engineered region 2 of sigmaE in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.45
  • 5OR5 · NMR structure of the complex formed by an engineered region 2 of sigmae in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.45
  • 6JBQ · Cryoem structure of escherichia COLI sigmae transcription initiation complex containing… · an experimental structure of the same protein · chain A against F, TM-score 0.44
  • 6JBQ · CryoEM structure of Escherichia coli sigmaE transcription initiation complex containing… · an experimental structure of the same protein · chain A against F, TM-score 0.44
  • 2H27 · Crystal structure of escherichia COLI sigmae region 4 bound to its-35 element DNA · an experimental structure of the same protein · chain A against D, TM-score 0.36
  • 2H27 · Crystal Structure of Escherichia coli SigmaE Region 4 Bound to its-35 Element DNA · an experimental structure of the same protein · chain A against D, TM-score 0.36

Analyse

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