MolNFT v1 · #387893 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit gamma (P14563)
P14563: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit gamma (P14563)”. 6 pockets (best druggability 0.50). MolNFT v1 #387893 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P14563
- Type
- protein
- Length
- 621 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5C2d59949384A437838d040D722C4476f3Dc82E4
- Molecule
- DNA-directed RNA polymerase subunit gamma
- UniProt
- P14563
- Pockets
- 6 · best druggability 0.50
Structure
1 distinct chain · 40% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase subunit gamma | protein | 621 | 40% helix, 18% strand | P14563 |
Pockets
6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 208 | 0.50 | 0.75 | 23 | empty |
| 2 | 181 | 0.49 | 0.76 | 28 | empty |
| 3 | 83 | 0.42 | 0.79 | 17 | empty |
| 4 | 97 | 0.36 | 0.74 | 15 | empty |
| 5 | 73 | 0.32 | 0.74 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P14563
- Elsewhere: UniProt P14563 · AlphaFold DB P14563
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