MolNFT v1 · #387854 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta' (P23580)
P23580: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta' (P23580)”. 6 pockets (best druggability 0.62). MolNFT v1 #387854 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P23580
- Type
- protein
- Length
- 586 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7012c0b45c68a2c067644b9d3e5DDa06892c6957
- Molecule
- DNA-directed RNA polymerase subunit beta'
- UniProt
- P23580
- Pockets
- 6 · best druggability 0.62
Structure
1 distinct chain · 44% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase subunit beta' | protein | 586 | 44% helix, 17% strand | P23580 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 255 | 0.62 | 0.80 | 27 | empty |
| 2 | 122 | 0.37 | 0.73 | 16 | empty |
| 3 | 96 | 0.36 | 0.75 | 18 | empty |
| 4 | 79 | 0.35 | 0.75 | 16 | empty |
| 5 | 82 | 0.34 | 0.74 | 17 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P23580
- Elsewhere: UniProt P23580 · AlphaFold DB P23580
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