MolNFT v1 · #386859 · protein

AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (Q31L30)

Q31L30: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (Q31L30)”. 4 pockets (best druggability 0.32). MolNFT v1 #386859 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q31L30
Type: protein
Length: 309 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x85B6B478711D4a6F442F2c82D8D795D37aDC473d
Molecule: DNA-directed RNA polymerase subunit alpha
UniProt: Q31L30
Pockets: 4 · best druggability 0.32

Structure

1 distinct chain · 26% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA-directed RNA polymerase subunit alpha	protein	309	26% helix, 34% strand	Q31L30

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	55	0.32	0.77	13	empty
2	64	0.32	0.76	16	empty
3	51	0.30	0.75	12	empty
4	53	0.29	0.75	15	empty

Compared structures

8SYI · Cyanobacterial RNAP-EC · an experimental structure of the same protein · chain A against A, TM-score 0.71
8URW · Cyanobacterial RNA polymerase elongation complex with NusG and CTP · an experimental structure of the same protein · chain A against A, TM-score 0.70

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q31L30
Elsewhere: UniProt Q31L30 · AlphaFold DB Q31L30

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