MolNFT v1 · #386806 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (P06505)
P06505: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (P06505)”. 5 pockets (best druggability 0.47). MolNFT v1 #386806 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P06505
- Type
- protein
- Length
- 335 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xC454Ee1D7BbEeEfB51BeDA473EEF401822a07027
- Molecule
- DNA-directed RNA polymerase subunit alpha
- UniProt
- P06505
- Pockets
- 5 · best druggability 0.47
Structure
1 distinct chain · 32% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase subunit alpha | protein | 335 | 32% helix, 31% strand | P06505 |
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 52 | 0.47 | 0.86 | 20 | empty |
| 2 | 136 | 0.45 | 0.76 | 17 | empty |
| 3 | 80 | 0.36 | 0.76 | 15 | empty |
| 4 | 75 | 0.34 | 0.75 | 15 | empty |
| 5 | 55 | 0.25 | 0.72 | 9 | empty |
Compared structures
- 8XZV · Architecture of the spinach plastid-encoded RNA polymerase · an experimental structure of the same protein · chain A against A, TM-score 0.65
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06505
- Elsewhere: UniProt P06505 · AlphaFold DB P06505
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