MolNFT v1 · #386640 · protein

AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (P0C500)

P0C500: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (P0C500)”. 5 pockets (best druggability 0.63). MolNFT v1 #386640 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P0C500
Type: protein
Length: 337 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x5881B09f2D8e743400698633641fc1cD2Ed2BE6F
Molecule: DNA-directed RNA polymerase subunit alpha
UniProt: P0C500
Pockets: 5 · best druggability 0.63

Structure

1 distinct chain · 28% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA-directed RNA polymerase subunit alpha	protein	337	28% helix, 32% strand	P0C500

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	215	0.63	0.83	26	empty
2	132	0.56	0.82	27	empty
3	65	0.46	0.83	21	empty
4	154	0.46	0.75	18	empty
5	64	0.35	0.78	11	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0C500
Elsewhere: UniProt P0C500 · AlphaFold DB P0C500

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