MolNFT v1 · #386240 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (Q8A4A2)
Q8A4A2: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (Q8A4A2)”. 4 pockets (best druggability 0.49). MolNFT v1 #386240 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8A4A2
- Type
- protein
- Length
- 330 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x88266F45E0832E38C9d906b86a6EE2d52e9cb6cC
- Molecule
- DNA-directed RNA polymerase subunit alpha
- UniProt
- Q8A4A2
- Pockets
- 4 · best druggability 0.49
Structure
1 distinct chain · 30% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase subunit alpha | protein | 330 | 30% helix, 29% strand | Q8A4A2 |
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 201 | 0.49 | 0.75 | 17 | empty |
| 2 | 86 | 0.41 | 0.78 | 17 | empty |
| 3 | 89 | 0.36 | 0.74 | 17 | empty |
| 4 | 61 | 0.30 | 0.74 | 12 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8A4A2
- Elsewhere: UniProt Q8A4A2 · AlphaFold DB Q8A4A2
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