MolNFT v1 · #386198 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (A1EA40)
A1EA40: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (A1EA40)”. 6 pockets (best druggability 0.60). MolNFT v1 #386198 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A1EA40
- Type
- protein
- Length
- 339 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xc9CEa587643029db290FCD395D0469b765A79a9A
- Molecule
- DNA-directed RNA polymerase subunit alpha
- UniProt
- A1EA40
- Pockets
- 6 · best druggability 0.60
Structure
1 distinct chain · 29% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase subunit alpha | protein | 339 | 29% helix, 32% strand | A1EA40 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 168 | 0.60 | 0.83 | 23 | empty |
| 2 | 135 | 0.55 | 0.81 | 19 | empty |
| 3 | 194 | 0.48 | 0.75 | 20 | empty |
| 4 | 122 | 0.40 | 0.75 | 19 | empty |
| 5 | 52 | 0.39 | 0.82 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A1EA40
- Elsewhere: UniProt A1EA40 · AlphaFold DB A1EA40
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