MolNFT v1 · #385783 · protein
AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN1 (Q6FPV6)
Q6FPV6: “AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN1 (Q6FPV6)”. 12 pockets (best druggability 0.83). MolNFT v1 #385783 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q6FPV6
- Type
- protein
- Length
- 983 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5881B09f2D8e743400698633641fc1cD2Ed2BE6F
- Molecule
- 26S proteasome regulatory subunit RPN1
- UniProt
- Q6FPV6
- Pockets
- 12 · best druggability 0.83
Structure
1 distinct chain · 57% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 26S proteasome regulatory subunit RPN1 | protein | 983 | 57% helix, 5% strand | Q6FPV6 |
Pockets
12 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1091 | 0.83 | 0.84 | 104 | empty |
| 2 | 340 | 0.78 | 0.89 | 50 | empty |
| 3 | 122 | 0.54 | 0.82 | 26 | empty |
| 4 | 149 | 0.47 | 0.77 | 17 | empty |
| 5 | 129 | 0.46 | 0.78 | 23 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6FPV6
- Elsewhere: UniProt Q6FPV6 · AlphaFold DB Q6FPV6
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