GL1X · GenesisL1 explorer

MolNFT v1 · #385770 · protein

AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN10 (O94444)

O94444: “AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN10 (O94444)”. 3 pockets (best druggability 0.39). MolNFT v1 #385770 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
O94444
Type
protein
Length
243 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x6BdE6afbf1E5F079b9F4169e9362dC26693b311A
Molecule
26S proteasome regulatory subunit RPN10
UniProt
O94444
Pockets
3 · best druggability 0.39

Structure

1 distinct chain · 44% helix, 17% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A26S proteasome regulatory subunit RPN10protein24344% helix, 17% strandO94444

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11100.390.7530empty
2610.310.7512empty
3680.290.7411empty

Compared structures

  • 2X5N · Crystal structure of the SPRPN10 vwa domain · an experimental structure of the same protein · chain A against A, TM-score 0.75
  • 2X5N · Crystal Structure of the SpRpn10 VWA domain · an experimental structure of the same protein · chain A against A, TM-score 0.75

Analyse

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