MolNFT v1 · #385069 · protein

AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit RPC3 (Q4WEU2)

Q4WEU2: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit RPC3 (Q4WEU2)”. 8 pockets (best druggability 0.82). MolNFT v1 #385069 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q4WEU2
Type: protein
Length: 629 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x9188600a0FCa2914254C94299b1bd9721Bc4D500
Molecule: DNA-directed RNA polymerase III subunit RPC3
UniProt: Q4WEU2
Pockets: 8 · best druggability 0.82

Structure

1 distinct chain · 52% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA-directed RNA polymerase III subunit RPC3	protein	629	52% helix, 8% strand	Q4WEU2

Pockets

8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	820	0.82	0.84	77	empty
2	104	0.70	0.93	24	empty
3	221	0.60	0.80	40	empty
4	113	0.54	0.83	17	empty
5	69	0.39	0.79	14	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4WEU2
Elsewhere: UniProt Q4WEU2 · AlphaFold DB Q4WEU2

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