MolNFT v1 · #385068 · protein

AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit RPC3 (A1C4R7)

A1C4R7: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit RPC3 (A1C4R7)”. 7 pockets (best druggability 0.74). MolNFT v1 #385068 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: A1C4R7
Type: protein
Length: 635 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xa73BAb1DabE4333A884D03393eAa10c3B4215494
Molecule: DNA-directed RNA polymerase III subunit RPC3
UniProt: A1C4R7
Pockets: 7 · best druggability 0.74

Structure

1 distinct chain · 53% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA-directed RNA polymerase III subunit RPC3	protein	635	53% helix, 8% strand	A1C4R7

Pockets

7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	904	0.74	0.78	68	empty
2	525	0.64	0.76	53	empty
3	166	0.54	0.79	31	empty
4	130	0.47	0.78	24	empty
5	97	0.38	0.75	20	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A1C4R7
Elsewhere: UniProt A1C4R7 · AlphaFold DB A1C4R7

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