MolNFT v1 · #385061 · protein

AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit RPC2 (P25167)

P25167: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit RPC2 (P25167)”. 18 pockets (best druggability 0.77). MolNFT v1 #385061 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P25167
Type: protein
Length: 1,137 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x738c1929c69B751bD0Be0B962D9bac20B631aAc6
Molecule: DNA-directed RNA polymerase III subunit RPC2
UniProt: P25167
Pockets: 18 · best druggability 0.77

Structure

1 distinct chain · 30% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA-directed RNA polymerase III subunit RPC2	protein	1137	30% helix, 26% strand	P25167

Pockets

18 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	526	0.77	0.84	57	empty
2	335	0.64	0.79	42	empty
3	267	0.56	0.77	26	empty
4	230	0.52	0.76	24	empty
5	140	0.51	0.80	19	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P25167
Elsewhere: UniProt P25167 · AlphaFold DB P25167

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