MolNFT v1 · #385054 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit RPC1 (P27625)
P27625: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit RPC1 (P27625)”. 20 pockets (best druggability 0.81). MolNFT v1 #385054 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P27625
- Type
- protein
- Length
- 2,339 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x362a6d063b1B7E1B6EfD3A9A7CA3612e3FE037AA
- Molecule
- DNA-directed RNA polymerase III subunit RPC1
- UniProt
- P27625
- Pockets
- 20 · best druggability 0.81
Structure
1 distinct chain · 34% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase III subunit RPC1 | protein | 2339 | 34% helix, 10% strand | P27625 |
Pockets
20 pockets found on a 1 Å grid, 17 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 535 | 0.81 | 0.87 | 55 | empty |
| 2 | 970 | 0.80 | 0.81 | 115 | empty |
| 3 | 499 | 0.77 | 0.84 | 49 | empty |
| 4 | 624 | 0.73 | 0.80 | 66 | empty |
| 5 | 756 | 0.72 | 0.78 | 56 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P27625
- Elsewhere: UniProt P27625 · AlphaFold DB P27625
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