MolNFT v1 · #385037 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB9 (O74635)
O74635: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB9 (O74635)”. 2 pockets (best druggability 0.42). MolNFT v1 #385037 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O74635
- Type
- protein
- Length
- 113 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x661f92Fc5950020C7aB410B5F5b9a3f429F49Ae5
- Molecule
- DNA-directed RNA polymerase II subunit RPB9
- UniProt
- O74635
- Pockets
- 2 · best druggability 0.42
Structure
1 distinct chain · 7% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase II subunit RPB9 | protein | 113 | 7% helix, 27% strand | O74635 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 71 | 0.42 | 0.80 | 16 | empty |
| 2 | 50 | 0.26 | 0.73 | 12 | empty |
Compared structures
- 3H0G · RNA Polymerase II from Schizosaccharomyces pombe · an experimental structure of the same protein · chain A against I, TM-score 0.84
- 3H0G · RNA polymerase II from schizosaccharomyces pombe · an experimental structure of the same protein · chain A against I, TM-score 0.84
- 5U0S · Cryo-EM structure of the Mediator-RNAPII complex · an experimental structure of the same protein · chain A against i, TM-score 0.84
- 5U0S · Cryo-EM structure of the mediator-rnapii complex · an experimental structure of the same protein · chain A against i, TM-score 0.84
- 8QSZ · Structure of s. pombe RNA polymerase II in complex with DSIF and Rat1/Rai1 · an experimental structure of the same protein · chain A against I, TM-score 0.78
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O74635
- Elsewhere: UniProt O74635 · AlphaFold DB O74635
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