MolNFT v1 · #385006 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB3 (P16370)
P16370: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB3 (P16370)”. 2 pockets (best druggability 0.38). MolNFT v1 #385006 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P16370
- Type
- protein
- Length
- 318 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0D671490EE06E75975e90D7F99F73B20BE618744
- Molecule
- DNA-directed RNA polymerase II subunit RPB3
- UniProt
- P16370
- Pockets
- 2 · best druggability 0.38
Structure
1 distinct chain · 25% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase II subunit RPB3 | protein | 318 | 25% helix, 25% strand | P16370 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 88 | 0.38 | 0.75 | 18 | empty |
| 2 | 75 | 0.33 | 0.75 | 16 | empty |
Compared structures
- 3GTK · Backtracked RNA polymerase II complex with 18mer RNA · an experimental structure of the same protein · chain A against C, TM-score 0.84
- 3GTG · Backtracked RNA polymerase II complex with 12mer RNA · an experimental structure of the same protein · chain A against C, TM-score 0.84
- 8K5P · Cryo-EM structure of yeast Rat1-bound Pol II pre-termination transcription complex 2 (Pol… · an experimental structure of the same protein · chain A against C, TM-score 0.84
- 3GTJ · Backtracked RNA polymerase II complex with 13mer RNA · an experimental structure of the same protein · chain A against C, TM-score 0.84
- 3I4N · 8-oxoguanine containing RNA polymerase II elongation complex E · an experimental structure of the same protein · chain A against C, TM-score 0.84
- 3I4M · 8-oxoguanine containing RNA polymerase II elongation complex D · an experimental structure of the same protein · chain A against C, TM-score 0.84
- 8JCH · Cryo-EM structure of yeast Rat1-bound Pol II pre-termination transcription complex 1 (Pol… · an experimental structure of the same protein · chain A against C, TM-score 0.84
- 6O6C · RNA polymerase II elongation complex arrested at a CPD lesion · an experimental structure of the same protein · chain A against C, TM-score 0.84
- 7UIO · Mediator-PIC Early (Composite Model) · an experimental structure of the same protein · chain A against AC, TM-score 0.84
- 7UI9 · Core Mediator-PICearly (Copy A) · an experimental structure of the same protein · chain A against C, TM-score 0.84
- 7UIF · Mediator-PIC Early (Core B) · an experimental structure of the same protein · chain A against C, TM-score 0.84
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16370
- Elsewhere: UniProt P16370 · AlphaFold DB P16370
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