MolNFT v1 · #385005 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB3 (P37382)
P37382: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB3 (P37382)”. 2 pockets (best druggability 0.53). MolNFT v1 #385005 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P37382
- Type
- protein
- Length
- 297 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x8649cEf8155c1DF9207d49fC28929aF3f84CBD40
- Molecule
- DNA-directed RNA polymerase II subunit RPB3
- UniProt
- P37382
- Pockets
- 2 · best druggability 0.53
Structure
1 distinct chain · 21% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase II subunit RPB3 | protein | 297 | 21% helix, 25% strand | P37382 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 281 | 0.53 | 0.75 | 34 | empty |
| 2 | 64 | 0.34 | 0.76 | 16 | empty |
Compared structures
- 8QSZ · Structure of s. pombe RNA polymerase II in complex with DSIF and Rat1/Rai1 · an experimental structure of the same protein · chain A against C, TM-score 0.87
- 3H0G · RNA polymerase II from schizosaccharomyces pombe · an experimental structure of the same protein · chain A against C, TM-score 0.86
- 3H0G · RNA Polymerase II from Schizosaccharomyces pombe · an experimental structure of the same protein · chain A against C, TM-score 0.86
- 5U0S · Cryo-EM structure of the Mediator-RNAPII complex · an experimental structure of the same protein · chain A against c, TM-score 0.86
- 5U0S · Cryo-EM structure of the mediator-rnapii complex · an experimental structure of the same protein · chain A against c, TM-score 0.86
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P37382
- Elsewhere: UniProt P37382 · AlphaFold DB P37382
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