MolNFT v1 · #384999 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB2 (Q42877)
Q42877: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB2 (Q42877)”. 19 pockets (best druggability 0.71). MolNFT v1 #384999 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q42877
- Type
- protein
- Length
- 1,191 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7AdE9AB197a9650d2B3aE28c73Eee20DfF832801
- Molecule
- DNA-directed RNA polymerase II subunit RPB2
- UniProt
- Q42877
- Pockets
- 19 · best druggability 0.71
Structure
1 distinct chain · 28% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase II subunit RPB2 | protein | 1191 | 28% helix, 25% strand | Q42877 |
Pockets
19 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 251 | 0.71 | 0.86 | 34 | empty |
| 2 | 250 | 0.62 | 0.81 | 31 | empty |
| 3 | 294 | 0.59 | 0.78 | 46 | empty |
| 4 | 305 | 0.58 | 0.77 | 28 | empty |
| 5 | 308 | 0.54 | 0.75 | 30 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q42877
- Elsewhere: UniProt Q42877 · AlphaFold DB Q42877
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