MolNFT v1 · #384989 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB2 (Q753Q4)
Q753Q4: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB2 (Q753Q4)”. 18 pockets (best druggability 0.78). MolNFT v1 #384989 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q753Q4
- Type
- protein
- Length
- 1,222 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xcD609cF0CC50806EC1C19a3758EC341c1825f7d4
- Molecule
- DNA-directed RNA polymerase II subunit RPB2
- UniProt
- Q753Q4
- Pockets
- 18 · best druggability 0.78
Structure
1 distinct chain · 29% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase II subunit RPB2 | protein | 1222 | 29% helix, 25% strand | Q753Q4 |
Pockets
18 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 811 | 0.78 | 0.81 | 74 | empty |
| 2 | 408 | 0.64 | 0.78 | 48 | empty |
| 3 | 229 | 0.62 | 0.82 | 30 | empty |
| 4 | 181 | 0.53 | 0.79 | 25 | empty |
| 5 | 264 | 0.52 | 0.75 | 26 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q753Q4
- Elsewhere: UniProt Q753Q4 · AlphaFold DB Q753Q4
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