MolNFT v1 · #384984 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB1 (P08775)
P08775: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB1 (P08775)”. 20 pockets (best druggability 0.85). MolNFT v1 #384984 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P08775
- Type
- protein
- Length
- 1,970 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xBF0D2e107Ce1EcD2C4369B042274201DB719AaAF
- Molecule
- DNA-directed RNA polymerase II subunit RPB1
- UniProt
- P08775
- Pockets
- 20 · best druggability 0.85
Structure
1 distinct chain · 30% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase II subunit RPB1 | protein | 1970 | 30% helix, 12% strand | P08775 |
Pockets
20 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1026 | 0.85 | 0.86 | 106 | empty |
| 2 | 884 | 0.79 | 0.82 | 98 | empty |
| 3 | 642 | 0.73 | 0.79 | 48 | empty |
| 4 | 329 | 0.65 | 0.81 | 46 | empty |
| 5 | 203 | 0.62 | 0.82 | 30 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P08775
- Elsewhere: UniProt P08775 · AlphaFold DB P08775
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