MolNFT v1 · #384981 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB1 (Q8SSC4)
Q8SSC4: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB1 (Q8SSC4)”. 20 pockets (best druggability 0.74). MolNFT v1 #384981 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8SSC4
- Type
- protein
- Length
- 1,599 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9cA7514A43Bc0E59A5d0B4962C8f176dB83A0526
- Molecule
- DNA-directed RNA polymerase II subunit RPB1
- UniProt
- Q8SSC4
- Pockets
- 20 · best druggability 0.74
Structure
1 distinct chain · 38% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase II subunit RPB1 | protein | 1599 | 38% helix, 14% strand | Q8SSC4 |
Pockets
20 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1081 | 0.74 | 0.77 | 80 | empty |
| 2 | 744 | 0.72 | 0.78 | 58 | empty |
| 3 | 789 | 0.70 | 0.76 | 74 | empty |
| 4 | 340 | 0.57 | 0.76 | 44 | empty |
| 5 | 306 | 0.55 | 0.76 | 32 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8SSC4
- Elsewhere: UniProt Q8SSC4 · AlphaFold DB Q8SSC4
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