MolNFT v1 · #384979 · protein

AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB1 (P35084)

P35084: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB1 (P35084)”. 20 pockets (best druggability 0.76). MolNFT v1 #384979 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P35084
Type: protein
Length: 1,727 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7B1Fbdc7c90598A502d8d8d5Dd726e011d0DC455
Molecule: DNA-directed RNA polymerase II subunit RPB1
UniProt: P35084
Pockets: 20 · best druggability 0.76

Structure

1 distinct chain · 36% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA-directed RNA polymerase II subunit RPB1	protein	1727	36% helix, 13% strand	P35084

Pockets

20 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1022	0.76	0.78	95	empty
2	513	0.73	0.82	47	empty
3	771	0.73	0.78	72	empty
4	718	0.72	0.78	63	empty
5	54	0.70	0.98	18	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P35084
Elsewhere: UniProt P35084 · AlphaFold DB P35084

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