MolNFT v1 · #384872 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases I, II, and III subunit RPABC1 (Q09191)
Q09191: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases I, II, and III subunit RPABC1 (Q09191)”. 2 pockets (best druggability 0.56). MolNFT v1 #384872 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q09191
- Type
- protein
- Length
- 210 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf635025d4b71bb1581df1a0b5A5a5eC99823AA86
- Molecule
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- UniProt
- Q09191
- Pockets
- 2 · best druggability 0.56
Structure
1 distinct chain · 42% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerases I, II, and III subunit RPABC1 | protein | 210 | 42% helix, 24% strand | Q09191 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 292 | 0.56 | 0.76 | 34 | empty |
| 2 | 51 | 0.32 | 0.77 | 17 | empty |
Compared structures
- 8QSZ · Structure of s. pombe RNA polymerase II in complex with DSIF and Rat1/Rai1 · an experimental structure of the same protein · chain A against E, TM-score 0.97
- 7AOD · Schizosaccharomyces pombe RNA polymerase I (dimer) · an experimental structure of the same protein · chain A against E, TM-score 0.94
- 7AOD · Schizosaccharomyces pombe RNA polymerase I (dimer) · an experimental structure of the same protein · chain A against E, TM-score 0.94
- 7AOC · Schizosaccharomyces pombe RNA polymerase I (monomer) · an experimental structure of the same protein · chain A against E, TM-score 0.94
- 7AOC · Schizosaccharomyces pombe RNA polymerase I (monomer) · an experimental structure of the same protein · chain A against E, TM-score 0.94
- 7AOE · Schizosaccharomyces pombe RNA polymerase I (elongation complex) · an experimental structure of the same protein · chain A against E, TM-score 0.93
- 7AOE · Schizosaccharomyces pombe RNA polymerase I (elongation complex) · an experimental structure of the same protein · chain A against E, TM-score 0.93
- 3H0G · RNA polymerase II from schizosaccharomyces pombe · an experimental structure of the same protein · chain A against E, TM-score 0.93
- 3H0G · RNA Polymerase II from Schizosaccharomyces pombe · an experimental structure of the same protein · chain A against E, TM-score 0.93
- 5U0S · Cryo-EM structure of the mediator-rnapii complex · an experimental structure of the same protein · chain A against e, TM-score 0.93
- 5U0S · Cryo-EM structure of the Mediator-RNAPII complex · an experimental structure of the same protein · chain A against e, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q09191
- Elsewhere: UniProt Q09191 · AlphaFold DB Q09191
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