MolNFT v1 · #384839 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase I subunit RPA2 (O74633)
O74633: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase I subunit RPA2 (O74633)”. 17 pockets (best druggability 0.78). MolNFT v1 #384839 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O74633
- Type
- protein
- Length
- 1,234 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x603786131b429eaC7e663e5851C902F5dCB72B70
- Molecule
- DNA-directed RNA polymerase I subunit RPA2
- UniProt
- O74633
- Pockets
- 17 · best druggability 0.78
Structure
1 distinct chain · 29% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase I subunit RPA2 | protein | 1234 | 29% helix, 24% strand | O74633 |
Pockets
17 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 656 | 0.78 | 0.83 | 80 | empty |
| 2 | 67 | 0.72 | 0.97 | 20 | empty |
| 3 | 81 | 0.61 | 0.89 | 22 | empty |
| 4 | 376 | 0.58 | 0.75 | 35 | empty |
| 5 | 153 | 0.53 | 0.80 | 20 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O74633
- Elsewhere: UniProt O74633 · AlphaFold DB O74633
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