MolNFT v1 · #384570 · protein

AlphaFold monomer V2.0 prediction for rop guanine nucleotide exchange factor 12 (Q9CA89)

Q9CA89: “AlphaFold monomer V2.0 prediction for rop guanine nucleotide exchange factor 12 (Q9CA89)”. 5 pockets (best druggability 0.75). MolNFT v1 #384570 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9CA89
Type: protein
Length: 515 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x4Ef77Afb5a3D9F41c95Be3227D1CC986CCb61835
Molecule: Rop guanine nucleotide exchange factor 12
UniProt: Q9CA89
Pockets: 5 · best druggability 0.75

Structure

1 distinct chain · 51% helix, 5% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Rop guanine nucleotide exchange factor 12	protein	515	51% helix, 5% strand	Q9CA89

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	936	0.75	0.78	70	empty
2	384	0.58	0.75	42	empty
3	98	0.46	0.79	16	empty
4	194	0.45	0.74	25	empty
5	84	0.36	0.75	16	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9CA89
Elsewhere: UniProt Q9CA89 · AlphaFold DB Q9CA89

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