MolNFT v1 · #384403 · protein

AlphaFold monomer V2.0 prediction for 1-pyrroline-5-carboxylate dehydrogenase 1 (Q9K9B2)

Q9K9B2: “AlphaFold monomer V2.0 prediction for 1-pyrroline-5-carboxylate dehydrogenase 1 (Q9K9B2)”. 3 pockets (best druggability 0.71). MolNFT v1 #384403 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9K9B2
Type: protein
Length: 515 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xB44F19a0cb161828322eEEd13F55d4C3C34938d2
Molecule: 1-pyrroline-5-carboxylate dehydrogenase 1
UniProt: Q9K9B2
Pockets: 3 · best druggability 0.71

Structure

1 distinct chain · 42% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	1-pyrroline-5-carboxylate dehydrogenase 1	protein	515	42% helix, 22% strand	Q9K9B2

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	352	0.71	0.83	51	empty
2	375	0.62	0.77	43	empty
3	62	0.31	0.75	18	empty

Compared structures

3QAN · Crystal structure of 1-pyrroline-5-carboxylate dehydrogenase from bacillus halodurans · an experimental structure of the same protein · chain A against A, TM-score 1.00
3QAN · Crystal structure of 1-pyrroline-5-carboxylate dehydrogenase from bacillus halodurans · an experimental structure of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9K9B2
Elsewhere: UniProt Q9K9B2 · AlphaFold DB Q9K9B2

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