MolNFT v1 · #381967 · protein

AlphaFold monomer V2.0 prediction for ribonuclease hiii (O67644)

O67644: “AlphaFold monomer V2.0 prediction for ribonuclease hiii (O67644)”. 2 pockets (best druggability 0.46). MolNFT v1 #381967 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: O67644
Type: protein
Length: 257 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x9F605311B7e26e76340423EfAfbE5e2EFc7A0b7C
Molecule: Ribonuclease hiii
UniProt: O67644
Pockets: 2 · best druggability 0.46

Structure

1 distinct chain · 47% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ribonuclease hiii	protein	257	47% helix, 21% strand	O67644

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	161	0.46	0.76	22	empty
2	110	0.39	0.75	19	empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

3VN5 · Crystal structure of Aquifex aeolicus RNase H3 · an experimental structure of the same protein · chain A against A, TM-score 0.71
3VN5 · Crystal structure of aquifex aeolicus RNase H3 · an experimental structure of the same protein · chain A against A, TM-score 0.71

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O67644
Elsewhere: UniProt O67644 · AlphaFold DB O67644

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