MolNFT v1 · #380745 · protein

AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase NRDP1 (Q9H4P4)

Q9H4P4: “AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase NRDP1 (Q9H4P4)”. 2 pockets (best druggability 0.29). MolNFT v1 #380745 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9H4P4
Type: protein
Length: 317 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x40B9C9d5F084D34d026E9d5Dd10501AcdF6d6152
Molecule: E3 ubiquitin-protein ligase NRDP1
UniProt: Q9H4P4
Pockets: 2 · best druggability 0.29

Structure

1 distinct chain · 47% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	E3 ubiquitin-protein ligase NRDP1	protein	317	47% helix, 15% strand	Q9H4P4

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	52	0.29	0.75	11	empty
2	58	0.27	0.73	11	empty

Compared structures

2FZP · Crystal structure of the USP8 interaction domain of human NRDP1 · an experimental structure of the same protein · chain A against A, TM-score 0.41
2FZP · Crystal structure of the USP8 interaction domain of human NRDP1 · an experimental structure of the same protein · chain A against A, TM-score 0.41
2GWF · Structure of a USP8-NRDP1 complex · an experimental structure of the same protein · chain A against D, TM-score 0.39
2GWF · Structure of a USP8-NRDP1 complex · an experimental structure of the same protein · chain A against D, TM-score 0.39

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9H4P4
Elsewhere: UniProt Q9H4P4 · AlphaFold DB Q9H4P4

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