MolNFT v1 · #379467 · protein

AlphaFold monomer V2.0 prediction for GDP-6-deoxy-D-mannose reductase (Q6T1X6)

Q6T1X6: “AlphaFold monomer V2.0 prediction for GDP-6-deoxy-D-mannose reductase (Q6T1X6)”. 2 pockets (best druggability 0.80). MolNFT v1 #379467 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q6T1X6
Type: protein
Length: 309 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x8FaEF14B1a3E454aE2Cf5074731A50b14d68F3ac
Molecule: GDP-6-deoxy-D-mannose reductase
UniProt: Q6T1X6
Pockets: 2 · best druggability 0.80

Structure

1 distinct chain · 44% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	GDP-6-deoxy-D-mannose reductase	protein	309	44% helix, 20% strand	Q6T1X6

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	538	0.80	0.87	66	empty
2	65	0.33	0.76	19	empty

Compared structures

2PK3 · Crystal structure of a GDP-4-keto-6-deoxy-D-mannose reductase · an experimental structure of the same protein · chain A against A, TM-score 1.00
2PK3 · Crystal Structure of a GDP-4-keto-6-deoxy-D-mannose reductase · an experimental structure of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6T1X6
Elsewhere: UniProt Q6T1X6 · AlphaFold DB Q6T1X6

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