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MolNFT v1 · #354349 · protein

AlphaFold monomer V2.0 prediction for 60S ribosomal protein L18A (Q02543)

Q02543: “AlphaFold monomer V2.0 prediction for 60S ribosomal protein L18A (Q02543)”. 1 pocket (best druggability 0.32). MolNFT v1 #354349 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q02543
Type
protein
Length
176 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xBeB220F0B5b0C48F46B5DDd3E3b071BC0827f8D6
Molecule
60S ribosomal protein L18A
UniProt
Q02543
Pockets
1 · best druggability 0.32

Structure

1 distinct chain · 22% helix, 32% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A60S ribosomal protein L18Aprotein17622% helix, 32% strandQ02543

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1670.320.7512empty

Compared structures

  • 8G5Y · mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) · an experimental structure of the same protein · chain A against LS, TM-score 0.99
  • 8G60 · mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) · an experimental structure of the same protein · chain A against LS, TM-score 0.99
  • 8A3D · Human mature large subunit of the ribosome with eIF6 and homoharringtonine bound · an experimental structure of the same protein · chain A against M, TM-score 0.99
  • 8G5Z · mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) · an experimental structure of the same protein · chain A against LS, TM-score 0.99
  • 8G6J · mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2) · an experimental structure of the same protein · chain A against LS, TM-score 0.99
  • 8GLP · mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus… · an experimental structure of the same protein · chain A against LS, TM-score 0.99
  • 8G61 · mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) · an experimental structure of the same protein · chain A against LS, TM-score 0.99
  • 9C3H · Structure of the CNOT3-bound human 80S ribosome with tRNA-ARG in the P-site. · an experimental structure of the same protein · chain A against LS, TM-score 0.99
  • 9GMO · eIF6-bound pre-60S large ribosomal subunit incorporating mutant uL16 · an experimental structure of the same protein · chain A against M, TM-score 0.99
  • 7XNX · High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells · an experimental structure of the same protein · chain A against LS, TM-score 0.99
  • 7OW7 · EIF6-bound large subunit of the human ribosome · an experimental structure of the same protein · chain A against M, TM-score 0.99
  • 7XNY · High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells · an experimental structure of the same protein · chain A against LS, TM-score 0.99

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