MolNFT v1 · #345914 · protein
AlphaFold monomer V2.0 prediction for regulating synaptic membrane exocytosis protein 2 (Q9UQ26)
Q9UQ26: “AlphaFold monomer V2.0 prediction for regulating synaptic membrane exocytosis protein 2 (Q9UQ26)”. 6 pockets (best druggability 0.46). MolNFT v1 #345914 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9UQ26
- Type
- protein
- Length
- 1,411 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xbb2F1C7CB3A1eeFAc24fCa72cc627162D5413FD7
- Molecule
- Regulating synaptic membrane exocytosis protein 2
- UniProt
- Q9UQ26
- Pockets
- 6 · best druggability 0.46
Structure
1 distinct chain · 11% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regulating synaptic membrane exocytosis protein 2 | protein | 1411 | 11% helix, 15% strand | Q9UQ26 |
Pockets
6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 103 | 0.46 | 0.79 | 20 | empty |
| 2 | 107 | 0.39 | 0.75 | 20 | empty |
| 3 | 121 | 0.38 | 0.74 | 20 | empty |
| 4 | 125 | 0.37 | 0.73 | 22 | empty |
| 5 | 60 | 0.28 | 0.73 | 14 | empty |
Compared structures
- 1V27 · Solution structure of the first C2 domain of RIM2 · an experimental structure of the same protein · chain A against A, TM-score 0.09
- 1V27 · Solution structure of the first C2 domain of RIM2 · an experimental structure of the same protein · chain A against A, TM-score 0.09
- 1WFG · PDZ domain of human RIM2B · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 1WFG · PDZ domain of human RIM2B · an experimental structure of the same protein · chain A against A, TM-score 0.08
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UQ26
- Elsewhere: UniProt Q9UQ26 · AlphaFold DB Q9UQ26
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