MolNFT v1 · #342925 · protein

AlphaFold monomer V2.0 prediction for transforming protein rhoa (P61589)

P61589: “AlphaFold monomer V2.0 prediction for transforming protein rhoa (P61589)”. 2 pockets (best druggability 0.49). MolNFT v1 #342925 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P61589
Type: protein
Length: 193 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x8FaEF14B1a3E454aE2Cf5074731A50b14d68F3ac
Molecule: Transforming protein rhoa
UniProt: P61589
Pockets: 2 · best druggability 0.49

Structure

1 distinct chain · 38% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transforming protein rhoa	protein	193	38% helix, 24% strand	P61589

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	115	0.49	0.80	29	empty
2	103	0.36	0.74	18	empty

Compared structures

3TVD · Crystal Structure of Mouse RhoA-GTP complex · an experimental structure of the same protein · chain A against A, TM-score 0.89
3TVD · Crystal structure of mouse rhoa-GTP complex · an experimental structure of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P61589
Elsewhere: UniProt P61589 · AlphaFold DB P61589

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