MolNFT v1 · #342623 · protein
AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 42 (A6NI28)
A6NI28: “AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 42 (A6NI28)”. 6 pockets (best druggability 0.61). MolNFT v1 #342623 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A6NI28
- Type
- protein
- Length
- 874 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x80D2ac0F5e3268bC5C1d28BBAA07E3169BB02b79
- Molecule
- Rho GTPase-activating protein 42
- UniProt
- A6NI28
- Pockets
- 6 · best druggability 0.61
Structure
1 distinct chain · 41% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Rho GTPase-activating protein 42 | protein | 874 | 41% helix, 9% strand | A6NI28 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 460 | 0.61 | 0.75 | 48 | empty |
| 2 | 399 | 0.60 | 0.76 | 34 | empty |
| 3 | 138 | 0.44 | 0.76 | 20 | empty |
| 4 | 87 | 0.36 | 0.76 | 19 | empty |
| 5 | 103 | 0.36 | 0.74 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A6NI28
- Elsewhere: UniProt A6NI28 · AlphaFold DB A6NI28
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