MolNFT v1 · #342619 · protein
AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 39 (P59281)
P59281: “AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 39 (P59281)”. 14 pockets (best druggability 0.80). MolNFT v1 #342619 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P59281
- Type
- protein
- Length
- 1,107 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB35df660264f41795De49C83276C108A4ba91ADE
- Molecule
- Rho GTPase-activating protein 39
- UniProt
- P59281
- Pockets
- 14 · best druggability 0.80
Structure
1 distinct chain · 28% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Rho GTPase-activating protein 39 | protein | 1107 | 28% helix, 4% strand | P59281 |
Pockets
14 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 754 | 0.80 | 0.84 | 64 | empty |
| 2 | 398 | 0.64 | 0.78 | 43 | empty |
| 3 | 298 | 0.60 | 0.78 | 27 | empty |
| 4 | 323 | 0.53 | 0.74 | 43 | empty |
| 5 | 261 | 0.52 | 0.75 | 22 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P59281
- Elsewhere: UniProt P59281 · AlphaFold DB P59281
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