MolNFT v1 · #342590 · protein

AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 27 (Q6ZUM4)

Q6ZUM4: “AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 27 (Q6ZUM4)”. 2 pockets (best druggability 0.41). MolNFT v1 #342590 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q6ZUM4
Type: protein
Length: 889 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x10b8B5E5d3b46d946b71325538B8cD55FCeb325e
Molecule: Rho GTPase-activating protein 27
UniProt: Q6ZUM4
Pockets: 2 · best druggability 0.41

Structure

1 distinct chain · 21% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Rho GTPase-activating protein 27	protein	889	21% helix, 14% strand	Q6ZUM4

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	101	0.41	0.77	17	empty
2	54	0.29	0.75	10	empty

Compared structures

3PP2 · Crystal structure of the pleckstrin homology domain of ArhGAP27 · an experimental structure of the same protein · chain A against A, TM-score 0.12
3PP2 · Crystal structure of the pleckstrin homology domain of ARHGAP27 · an experimental structure of the same protein · chain A against A, TM-score 0.12

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6ZUM4
Elsewhere: UniProt Q6ZUM4 · AlphaFold DB Q6ZUM4

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