MolNFT v1 · #342570 · protein

AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 20 (Q9P2F6)

Q9P2F6: “AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 20 (Q9P2F6)”. 9 pockets (best druggability 0.68). MolNFT v1 #342570 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9P2F6
Type: protein
Length: 1,191 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x5dd626f16fC7Acc5015B8186FbddEF75B2353a2e
Molecule: Rho GTPase-activating protein 20
UniProt: Q9P2F6
Pockets: 9 · best druggability 0.68

Structure

1 distinct chain · 21% helix, 7% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Rho GTPase-activating protein 20	protein	1191	21% helix, 7% strand	Q9P2F6

Pockets

9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	673	0.68	0.76	58	empty
2	438	0.59	0.75	44	empty
3	314	0.56	0.76	30	empty
4	120	0.50	0.80	19	empty
5	87	0.37	0.76	15	empty

Compared structures

3MSX · Crystal structure of RhoA.GDP.MgF3 in complex with GAP domain of ArhGAP20 · an experimental structure of the same protein · chain A against B, TM-score 0.16
3MSX · Crystal structure of RHOA.GDP.MGF3 in complex with gap domain of ARHGAP20 · an experimental structure of the same protein · chain A against B, TM-score 0.16

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9P2F6
Elsewhere: UniProt Q9P2F6 · AlphaFold DB Q9P2F6

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