MolNFT v1 · #342524 · protein

AlphaFold monomer V2.0 prediction for GTP-binding protein rheb (Q62639)

Q62639: “AlphaFold monomer V2.0 prediction for GTP-binding protein rheb (Q62639)”. 2 pockets (best druggability 0.51). MolNFT v1 #342524 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q62639
Type: protein
Length: 184 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xda78dc0067231e8868637919D98AF298D7Df540C
Molecule: GTP-binding protein rheb
UniProt: Q62639
Pockets: 2 · best druggability 0.51

Structure

1 distinct chain · 39% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	GTP-binding protein rheb	protein	184	39% helix, 26% strand	Q62639

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	159	0.51	0.79	31	empty
2	89	0.35	0.74	19	empty

Compared structures

2L0X · Solution structure of the 21 kda GTPase rheb bound to GDP · an experimental structure of the same protein · chain A against A, TM-score 0.77
2L0X · Solution structure of the 21 kDa GTPase RHEB bound to GDP · an experimental structure of the same protein · chain A against A, TM-score 0.77

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q62639
Elsewhere: UniProt Q62639 · AlphaFold DB Q62639

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