MolNFT v1 · #342513 · protein
AlphaFold monomer V2.0 prediction for inactive rhomboid protein 2 (A0JPA1)
A0JPA1: “AlphaFold monomer V2.0 prediction for inactive rhomboid protein 2 (A0JPA1)”. 9 pockets (best druggability 0.78). MolNFT v1 #342513 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A0JPA1
- Type
- protein
- Length
- 826 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xBeB220F0B5b0C48F46B5DDd3E3b071BC0827f8D6
- Molecule
- Inactive rhomboid protein 2
- UniProt
- A0JPA1
- Pockets
- 9 · best druggability 0.78
Structure
1 distinct chain · 34% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Inactive rhomboid protein 2 | protein | 826 | 34% helix, 8% strand | A0JPA1 |
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 529 | 0.78 | 0.85 | 56 | empty |
| 2 | 682 | 0.74 | 0.80 | 69 | empty |
| 3 | 427 | 0.66 | 0.79 | 36 | empty |
| 4 | 199 | 0.64 | 0.84 | 27 | empty |
| 5 | 153 | 0.54 | 0.81 | 25 | empty |
Modifications
Observed in the structure: 9 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0JPA1
- Elsewhere: UniProt A0JPA1 · AlphaFold DB A0JPA1
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