MolNFT v1 · #342512 · protein
AlphaFold monomer V2.0 prediction for inactive rhomboid protein 2 (Q80WQ6)
Q80WQ6: “AlphaFold monomer V2.0 prediction for inactive rhomboid protein 2 (Q80WQ6)”. 6 pockets (best druggability 0.84). MolNFT v1 #342512 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q80WQ6
- Type
- protein
- Length
- 827 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x3Fb036B69Ae373B7B8D5715E6f811A5c94260042
- Molecule
- Inactive rhomboid protein 2
- UniProt
- Q80WQ6
- Pockets
- 6 · best druggability 0.84
Structure
1 distinct chain · 34% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Inactive rhomboid protein 2 | protein | 827 | 34% helix, 7% strand | Q80WQ6 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1060 | 0.84 | 0.85 | 131 | empty |
| 2 | 198 | 0.68 | 0.86 | 26 | empty |
| 3 | 177 | 0.56 | 0.81 | 27 | empty |
| 4 | 173 | 0.56 | 0.80 | 25 | empty |
| 5 | 76 | 0.32 | 0.75 | 15 | empty |
Modifications
Observed in the structure: 9 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q80WQ6
- Elsewhere: UniProt Q80WQ6 · AlphaFold DB Q80WQ6
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