MolNFT v1 · #342506 · protein
AlphaFold monomer V2.0 prediction for inactive rhomboid protein 1 (Q6PIX5)
Q6PIX5: “AlphaFold monomer V2.0 prediction for inactive rhomboid protein 1 (Q6PIX5)”. 9 pockets (best druggability 0.74). MolNFT v1 #342506 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q6PIX5
- Type
- protein
- Length
- 856 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7bdd87d2Db5fa3f4F529292a2FA2d019352c558a
- Molecule
- Inactive rhomboid protein 1
- UniProt
- Q6PIX5
- Pockets
- 9 · best druggability 0.74
Structure
1 distinct chain · 33% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Inactive rhomboid protein 1 | protein | 856 | 33% helix, 7% strand | Q6PIX5 |
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 729 | 0.74 | 0.80 | 66 | empty |
| 2 | 361 | 0.72 | 0.84 | 55 | empty |
| 3 | 309 | 0.72 | 0.85 | 37 | empty |
| 4 | 242 | 0.71 | 0.86 | 31 | empty |
| 5 | 234 | 0.62 | 0.81 | 27 | empty |
Modifications
Observed in the structure: 10 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6PIX5
- Elsewhere: UniProt Q6PIX5 · AlphaFold DB Q6PIX5
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