MolNFT v1 · #341756 · protein

AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 7 (O46470)

O46470: “AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 7 (O46470)”. 4 pockets (best druggability 0.79). MolNFT v1 #341756 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: O46470
Type: protein
Length: 469 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7a1388B6Aad67B04634A32f63b8A6D6005eab86c
Molecule: Regulator of G-protein signaling 7
UniProt: O46470
Pockets: 4 · best druggability 0.79

Structure

1 distinct chain · 56% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Regulator of G-protein signaling 7	protein	469	56% helix, 4% strand	O46470

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	934	0.79	0.81	83	empty
2	75	0.49	0.83	17	empty
3	105	0.48	0.80	19	empty
4	154	0.46	0.76	26	empty

Compared structures

6N9G · Crystal Structure of RGS7-Gbeta5 dimer · an experimental structure of the same protein · chain A against B, TM-score 0.80
6N9G · Crystal structure of RGS7-GBETA5 dimer · an experimental structure of the same protein · chain A against B, TM-score 0.80

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O46470
Elsewhere: UniProt O46470 · AlphaFold DB O46470

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